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Buy Codopyrin GlaxoSmithKline (GSK) Online


Buy Online Codopyrin GlaxoSmithKline (GSK) without prior prescription


Codopyrin

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CODOPYRIN

Brand:
CODOPYRIN

Manufacturer:
GLAXO SMITH KLINE

Compositions:
Aspirin 250mg, Paracetamol 250mg, Codiene 1% tabs,

DRUG INTERACTION:
Aspirin/paracetamol
Alcohol, corticosteroids, analgin, phenylbutazone may increae risk of GI ulceration.
Aspirin increases phenytoin levels.
May antogonise actions of uricosurics and spironolactone
May potentiate effects of anticogulants, methotrexate and oral hypoglycemics
Codeine- Alcohol, MAOIs CNS depressants, Phenytoin

ADVERSE REACTION:
Aspirin/paracetamol
GI disturbances, prolonged bleeding time, rhinitis, urticaria and epigastric discomfort Angioedema, salicylism, tinnitus, bronchospasm Gastric erosion, ulceration and bleeding Severe fatal exacerbation of airway obstruction in asthma
Reyes syndrome (children< 12 years ) Hepatoxicity CNS depression which may lead to coma. CV collapse and respiratory failure. Paroxymal bronchospasm and dyspnoea.
Codeine
Drowsiness, impaired reactions, constipation Nausea, dryness of the mouth, depedence, addition, blurred vision, Headache, dizziness, fatigue, Attention disturbances,
Respiratory depression in sensitive patients or if given in large doses.

CONTRA-INDICATIONS:
Aspirin/Paracetamol
Hypersentivity - (attacks of asthma, angioedema, urticaria or rhinitis ) Activre peptic ulceration Pregnancy (3rd trimester) Child < 12 years) Patients with haemophillia or haemorsrhagic disorders Gout. Severe renal or hepatic impairment Lactation.
Special precauions-
Histrory of peptic ulcer or those prone to dyspepsia and those with gastric mucosal lesion, Asthma or allergic disorders
Dehydrated patients,
Uncontrolled hypertension,
Impaired renal or hepatic function.
Elderly
Codeine
Liver disease, ventilatory failure Lactation
Special precautions-
Asthma, bronchitis, bronchiiectasis, hepatic or renal impairment
Children.
Driving or operating machinery
Epliepsy
Raised IOP,
BPH, severe hypertension Cardiovascular disesase,
Thyrotoxicosis. Elderly Pregnancy

DOSAGES/ OVERDOSAGE ETC:
Indication
Mild to moderate pain and fever

Dosage
Aspirin Child- 80-100mg/kg daily in 5 or 6 divided dose Upto 130mg/kg/ daily in acute excerbations if necessary
Pain/inflamtion- adult- initial 2.4- to3.6 g/day in divided doses. Maintenance - 3.6 to 5.4 g /day . Monitor serum concentrates
Mild to moderate pain Adult- initial - 325-650mg repeated every 4- 6 hr acccording to response. Max 4g/day also be given

PREGNANCY AND LACTATION:
Contrindicated for use during pregnancy and lactation
Observe caution if use is needed.

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