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BRICAREX

DRUG INTERACTION:
Bronchodilators - include Albuterol, Biotolterol, Ephedrine,Ephinephrine, Ethylnorepinephrine, Isoetharine, Isoproterrenol, Metaproterenol, Pirbuterol, Salmeterol, Terbutaline Refer- Ephedrine- Inhalation

Improved respiratory function when combined with beclomethasone, theophylline. Action of sympathomimetic bronchodilators inhibited by beta-blockers. Food reduces bio-availability.

INTERACTION WITH FOOD:
Refer sympathomimetics- bronchodilators

PREGNANCY AND LACTATION:
Refer sympathomimetics- broncodilators

ADVERSE REACTION:
Very rare, pulmonary oedema (during pregnancy). Fine skeletal muscle tremor, especially in hands, tachycardia, palpitations, peripheral vasodilatation, hypotension, nausea, headache, drowsiness, nervousness. Tolerance. Inhalation: If usual dose does not provide relief, non-responsive state may develop in which case aerosol may prove harmful (worsening of hypoxemia). Swallowing of inhalation may cause epigastric pain.

CONTRA-INDICATIONS:
Hypersens to sympathomimetic amines. Cardiac patients with associated arrhythmias. After antipartun haemorrhage, toxemia of pregnancy. Special precautions: Hypertension. Hyperthyroidism. Cardiac patients, pregnancy.

DOSAGES/ OVERDOSAGE ETC:
Indications: Bronchial asthma Dosage: Inhalation adults and children below 12 years- 2 inhalations separated by 60 seconds every 4 to 6 hours. Do not repeat more often than every 4 to 6 hours. Oral- adults and children below 15 years- 5 mg given at 6 hours intervals, 3 times daily during waking hours. If side effects are produced the dose may be decreased. Not recommended for children below 12 years of age.

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