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Bronchodilators - include Albuterol, Biotolterol, Ephedrine,Ephinephrine, Ethylnorepinephrine, Isoetharine, Isoproterrenol, Metaproterenol, Pirbuterol, Salmeterol, Terbutaline Refer- Ephedrine- Inhalation
Improved respiratory function when combined with beclomethasone, theophylline. Action of sympathomimetic bronchodilators inhibited by beta-blockers. Food reduces bio-availability.
INTERACTION WITH FOOD:
Refer sympathomimetics- bronchodilators
PREGNANCY AND LACTATION:
Refer sympathomimetics- broncodilators
Very rare, pulmonary oedema (during pregnancy). Fine skeletal muscle tremor, especially in hands, tachycardia, palpitations, peripheral vasodilatation, hypotension, nausea, headache, drowsiness, nervousness. Tolerance. Inhalation: If usual dose does not provide relief, non-responsive state may develop in which case aerosol may prove harmful (worsening of hypoxemia). Swallowing of inhalation may cause epigastric pain.
Hypersens to sympathomimetic amines. Cardiac patients with associated arrhythmias. After antipartun haemorrhage, toxemia of pregnancy. Special precautions: Hypertension. Hyperthyroidism. Cardiac patients, pregnancy.
DOSAGES/ OVERDOSAGE ETC:
Indications: Bronchial asthma Dosage: Inhalation adults and children below 12 years- 2 inhalations separated by 60 seconds every 4 to 6 hours. Do not repeat more often than every 4 to 6 hours. Oral- adults and children below 15 years- 5 mg given at 6 hours intervals, 3 times daily during waking hours. If side effects are produced the dose may be decreased. Not recommended for children below 12 years of age.
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