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CLOFOZINE

Generic Name
Clofazimine

Why it is prescribed (Indications):
This medication is an anti-inflammatory agent, prescribed for leprosy with other drugs. It is also used to treat reactions to anti ?? leprosy drugs.

When it is to be taken:
Multibacillary Leprosy treatment: 50 mg daily plus 300 mg once a month along with other antileprosy drugs for 1 year.
Reactions in Leprosy: Treatment depends on severity. 100-200 mg/day for up to 3 month.

How it should be taken:
It comes as a capsule to take by mouth once a day, with or without food.

Warnings and Precautions:
- It may cause dizziness, drowsiness. Do not drive a car or operate machinery while taking this medication.
- It may cause a red to brownish black discoloration of skin, mucous membranes and secretions.
- Avoid direct sunlight; wear protective clothing, including a hat. Also, wear sunglasses.
- Caution needed for patients with GI symptoms, liver and kidney damage and during pregnancy.

Side Effects:
Skin- Pigmentation from pink to brownish-black, scaly skin and dryness, rash and itching.
Gastrointestinal- Abdominal pain, diarrhea, nausea, vomiting, gastrointestinal intolerance.
Eye- Discoloration of cornea and conjunctiva along with dryness and irritation of the eyes.
Other- Discoloration of urine, feces, sputum, sweat, elevated blood sugar, elevated ESR(erythrocyte sedimentation rate).
Central Nervous System- Dizziness, drowsiness, fatigue, headache, giddiness, nerve pain, taste disorder.

Other Precautions :
- Do not change the dosage without your doctor's advice.

Storage Conditions:
Oral: Store below 30?C. Store it in airtight container and keep away from children.

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